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Kim Good-Jacobson

@KimLJacobson

Immunologist; Head of B cells, Antibody, Memory lab.
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Non-lab life alias: Kim Jacobson. Views my own.
Melbourne, Victoria monash.edu/discovery-inst… Joined February 2013
787 Following 1.7K Followers 1.1K Posts

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Kim Good-Jacobson @KimLJacobson
I am very excited to see this in print!

New work from our lab defines an interferon-induced memory B cell subset during chronic viral infection.

An awesome effort by Lucy Cooper @coopernatant & supported by our generous lab members & collaborators

@MonashBDI @ImmunityCP
Immunity @ImmunityCP Apr 8, 2024
Online now: Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection dlvr.it/T5DpCg
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Kim Good-Jacobson @KimLJacobson
Great to see this out! Following on from our earlier work revealing DOT1L was essential for humoral responses, here we determine the importance of H3K79me2 at multiple stages of B cell biology
👏 to Liam for tenaciously driving this study
👏 to collabs @sjturn + those not on X
DOT1L-mediated H3K79me2 directs B-cell repertoire establishment, marginal zone development, and germinal center function @J_Immunol @KimLJacobson @MonashUni 🇦🇺
academic.oup.com/jimmunol/advan…
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Kim Good-Jacobson @KimLJacobson
It's great to see this out today! A tour de de force by @MasatoOgishi Koji Kitaoka, @casanova_lab, @Tangye_Lab + others...

Also stoked to contribute unpublished recall response data from my postdoc a very long time ago 🙂
Masato OGISHI @MasatoOgishi Nov 26, 2024
1/ We report @ImmunityCP that the PD-1:PD-L1 axis promotes the development of B-cell memory and antibody responses in mice and humans. To our surprise, the pro-B-cell effect of PD-1 and PD-L1 is, at least partially, mediated in a B-cell-intrinsic manner. cell.com/immunity/abstr…
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