KnowlesLab Cambridge

Our latest paper by @Catherine_k_xu
- secondary nucleation is the source of both oligomers and fibrils in Parkinson's associated a-Synuclein aggregation. Fantastic collaboration with Linse lab
@SpillantiniLab and @VendruscoloLab
nature.com/articles/s4146…

Thermodynamic insights into trigger factor broad substrate specificity - fantiastic work by Therese together with Quentin, Pavan, Tadas and @SchneiderMatth in a collaboration with Christodoulou and Cabrita groups at UCL is out now:

science.org/doi/10.1126/sc…

Introducing a quantitative nonspecificity score for clinical-stage antibodies - great work by Therese Herling and @HAusserwoeger in an exciting collaboration with Novo Nordisk is now published:

pnas.org/doi/10.1073/pn…

Fundamental insights into the influence of sheer forces in amyloid formation - great work by @eaandrzejewska and @mus_greta led by @Emil_Axell and others from the Linse lab is now out:
pnas.org/doi/10.1073/pn…

Check out our newest publication on creating custom architectures inside biomolecular condensates - congratulations Nadia, @DaoyuanQian219, Tomas and others together with the Weitz lab and @vanhest_lab!
nature.com/articles/s4428…