Ligand-Transformer enables sequence-based drug design by building on the success of the AlphaFold transformer architecture in predicting protein structures. Notably, with this approach disordered proteins can be targeted for drug design.
biorxiv.org/content/10.110…
biorxiv.org/content/10.110…
www.biorxiv.org Sequence-based drug design using transformers Protein-ligand interactions play central roles in biological processes and are of key importance in drug design. Deep learning-based approaches are emerging as cost-effective alternatives to high-t... 
