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Excited to share our new study in Cell Host & Microbe!
We show that bacteria in human saliva and the small intestine can metabolize peanut allergens, reducing IgE binding and anaphylaxis.
Patients with higher peanut tolerance harbor more of these microbes. 1/2
We show that bacteria in human saliva and the small intestine can metabolize peanut allergens, reducing IgE binding and anaphylaxis.
Patients with higher peanut tolerance harbor more of these microbes. 1/2
Microbiota impact peanut allergyView quoted post on X
Saliva & jejunum harbor peanut-degrading bacteria(Rothia) that metabolize immunodominant PN allergens. Mice colonized w/Rothia show ⬇️anaphylaxis & allergic patients w/better PN tolerance have ⬆️abundance of these bacteria
cell.com/cell-host-micr…
