MearsLab

@LabMears

We study mitochondrial dynamics using structural, functional, and cellular methods.

Cleveland, OH pharmacology.case.edu/department/fac… Joined June 2018

170 Following 173 Followers 119 Posts

Latest posts 5

MearsLab @LabMears Apr 5, 2024

Happy to share new structure of the Drp1 lattice on a membrane. Great collaboration with @sstaggal using RASTR method. Ray and @KristyRochon did an amazing job pulling this together.
biorxiv.org/content/10.110…

www.biorxiv.org The Structure of the Drp1 Lattice on Membrane Mitochondrial health relies on the membrane fission mediated by dynamin-related protein 1 (Drp1). Previous structural studies of Drp1 on remodeled membranes were hampered by heterogeneity, leaving a...

MearsLab @LabMears Feb 13, 2024

Kristy's Drp1 dimer structure is officially out! Yes, the mitochondrial fission protein is very dynamic, and novel conformations regulate assembly and function.

Thanks to @DTaylorLab, Yu and Ramachandran Labs for your contributions.

rdcu.be/dywTF

MearsLab @LabMears Feb 10, 2024

Special treat to hear from Jenny as she receives the Katz Award in the Membrane Fission, Fusion and Traffic subgroup at #BPS2024.

MearsLab @LabMears Feb 10, 2024

Always fun being back at #BPS2024. Be sure to visit Anelise and Yuli on Sunday and Wednesday…

MearsLab @LabMears Dec 7, 2023

@KristyRochon did a fantastic job with her thesis defense today. Big congratulations and celebration for DR. Rochon 🍾🎉