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RewitzLab

@LabRewitz

We use the model insect Drosophila melanogaster to study totes dope hormonal regulation of growth & development, as well as models of neuropsychatric disorders.
Copenhagen, Denmark rewitzlab.dk Joined July 2019
222 Following 542 Followers 179 Posts

Latest posts 5

RewitzLab @LabRewitz
Why do we feel sleepy when sick, and how does gut health affect sleep? 🤒💤
Our new eLife study shows that gut inflammation signals to the brain to trigger sleep.
👉 doi.org/10.7554/eLife.…
#Neuroscience #SleepResearch #GutBrainAxis
elifesciences.org Glia-mediated gut–brain cytokine signaling couples sleep to intestinal inflammatory responses... Gut-to-brain communication via glial cytokine signaling links intestinal oxidative stress to altered sleep patterns, highlighting how gut inflammation can influence brain function and restorative...
RewitzLab @LabRewitz
We are thrilled to share that @eLife has now published our "reviewed preprint" on how signaling from the gut to glia connects intestinal inflammation to sleep in #Drosophila!
elifesciences.org/reviewed-prepr…
@HalbergLab @Colombani_lab @lundbeckfonden @novonordiskfond @Carlsbergfondet
RewitzLab @LabRewitz Jul 10, 2024
We are excited to share our recent work on gut-to-glia communication linking intestinal inflammation with sleep in #Drosophila! Many thanks to @HalbergLab and Andersen and @Colombani_lab!

@lundbeckfonden @novonordiskfond @Carlsbergfondet @UCPH_Research

biorxiv.org/content/10.110…
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1 replies 15 reposts 46 likes 13K views View on X
RewitzLab @LabRewitz
Thrilled to share our work! Thanks to @NovoNordiskFond and @DFF_raad, we unveil how LGR signaling mediates crosstalk between muscle, neuronal, and adipose tissues, protecting against #insulinresistance and offering insights into #Diabetes and #Obesity.

nature.com/articles/s4146…
www.nature.com LGR signaling mediates muscle-adipose tissue crosstalk and protects against diet-induced insulin... Nature Communications - Obesity induces insulin resistance and impairs insulin signaling, causing diabetes. Here, the authors show that BMP and LGR signaling mediate communication between muscle,...
0 replies 10 reposts 19 likes 2K views View on X
RewitzLab @LabRewitz
Our preprint on #Obesity-driven #InsulinResistance reveals a muscle-neuronal-fat axis adapting to high-sugar-induced obesity conditions by influencing insulin secretion & sensitivity in #Drosophila. @Halberglab biorxiv.org/content/10.110…
www.biorxiv.org A neuronal relay mediates muscle-adipose communication that drives systemic metabolic adaptation to... Obesity leads to impaired insulin signaling and tissue sensitivity, which drive the onset of type 2 diabetes. Insulin resistance leads to a reduction in cellular glucose uptake, resulting in elevated...