The ECM isn’t just an innocent bystander...
We join forces with @bitonslab in this new @bioaRxivpreprint on how lasting #ECM damage, “modECM”, pushes intestinal stem cells into a wound associated pro-inflammatory state!
biorxiv.org/content/10.110…
We join forces with @bitonslab in this new @bioaRxivpreprint on how lasting #ECM damage, “modECM”, pushes intestinal stem cells into a wound associated pro-inflammatory state!
biorxiv.org/content/10.110…
www.biorxiv.org Persistent ECM Scarring Reprograms Intestinal Stem Cells to Drive Chronic Inflammation Tissue regeneration is conventionally viewed as a return to homeostasis. Here, we uncover that the extracellular matrix (ECM) in the colon undergoes a lasting pathological reprogramming following... 
