Excited to share our new paper, out today in @ScienceMagazine! We developed senescence-modulating nanoparticles (SMNPs) that target P-selectin+ pathogenic senescent-like macrophages in fibrotic tissues and tumors.
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
www.science.org Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer Fibrotic remodeling of tissues and tumors establishes immunosuppressive microenvironments that drive organ dysfunction and, in cancer, limit response to immunotherapy. Senescent-like cells are... 
