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Marcin J. Suskiewicz
@MSuskiewicz
Structural biologist and biochemist. CNRS researcher at CBM Orléans. Interested in protein modifications & interactions. Also husband, dad of 3, friend, ☧.
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Happy to share our preprint on a subset of ZBTB BTB domains as efficient natural SUMO 'supersubstrates'. The work was spearheaded by a great postdoc, El Hadji Cisse, with input from other team members and in collaboration with Defossez and Aucagne labs. biorxiv.org/content/10.648…
I feel there are more points of division at play: utilitarian (things matter if they serve the right goal, ultimately the pleasure/health of individuals) vs. attentive to inherent value; individualist vs. communitarian; universalist (global wellbeing) vs. localist (a web of...
I wonder how much of the divide among mathematicians on AI comes down to which of us consider ourselves scientists and which of us consider ourselves artists. (I'm very much in the former camp but for what it's worth I am sympathetic to the latter.)View quoted post on X
I follow the AI & math discourse a bit - without understanding the actual math. I thought I might offer some thoughts as a scientist in structural biology - a field transformed by various tech over the years, and recently by AlphaFold. It might perhaps interest @nasqret et al.🧵
I'm currently returning to Toronto from a summit on the future of mathematics, at OpenAI. @SebastienBubeck asked me to talk a bit about the future we'd all like to avoid, where humans are mathematically disempowered. @Jacob_Tsimerman advised us to try to prioritize detail over correctness, and I have no doubt that I succeeded in deprioritizing correctness.
I tried to find a title that wasn't too bombastic:View quoted post on X
Nice to see this interesting preprint published in the final form. Will read it. Congratulations to Authors
Large-scale quaternary structural transitions underlie gain of function of SPOP cancer mutations dlvr.it/TTxsZgView quoted post on X
