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Marcus Goncalves

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@MarcusDGon

MD/PhD Endocrinologist Scientist. Cancer metabolism, cachexia, insulin, PI3K, diabetes, obesity. GI Villi lover. Metabolic Consulting. NYJ/NYY/NYCFC/NYK fan.
New York goncalveslab.com Joined April 2009
773 Following 2.9K Followers 7K Posts

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Marcus Goncalves Verified account @MarcusDGon
Going to mention this finding to all my low T consults who want to “optimize” their levels for “wellness” and “longevity”
Science Magazine Verified account @ScienceMagazine 4d
If they dared, biohacking bros who seek to defy aging could try a simple, time-tested method: castration.

Removing the testicles extends male life span across many mammalian species, including humans. But a research team exploring this effect has now found the surgical procedure doesn’t have to be performed early in life to boost longevity, as scientists had assumed.

In a new preprint, the group reports that neutering older male mice lengthens their lives by more than 30%, upending prevailing ideas of how the testes influence aging.

Learn more: scim.ag/4zs7KPX @NewsfromScience
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Marcus Goncalves Verified account @MarcusDGon
Retatrutide beats Ozempic head to head. TRANSCEND-T2D-2, 80 weeks: A1c down 2.2 points vs 1.8, weight down 20.9% vs 9.4% at 12 mg. Triple agonist, still investigational. Topline only, not yet peer reviewed. investor.lilly.com/news-releases/…
investor.lilly.com Lilly's retatrutide delivered greater A1C reduction and more than double the weight loss of... The Investor Relations website contains information about Eli Lilly and Company's business for stockholders, potential investors, and financial analysts.