Chris Thompson, MD (@MetabolicEndo)

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Chris Thompson, MD @MetabolicEndo Sep 22

The gut is much more than a digestive organ. It is a metabolic sensing and signaling system that helps shape how we respond to food, regulate appetite, and control metabolism.

Really enjoyed going deep on this with Andrew Huberman, from gut biology and the microbiome to obesity, GLP-1 therapies, and endoscopic treatments.

Andrew D. Huberman, Ph.D. Verified account @hubermanlab Sep 21

The new Huberman Lab episode is out: Best Tools for Gut Health and Weight Loss | Dr. Chris Thompson

0:00 Dr. Chris Thompson
2:16 Digestive Tract, Gut Hormones & Nutrient Absorption
8:06 Colon Microbiome & Colon Cancer Screening
11:13 Sponsors: LMNT & Lingo
13:40 Swallowing Problems & Zenker's Diverticula
16:08 Bowel Movements & Constipation
18:28 Fiber, Resistant Starch & the Gut Barrier
21:50 Intermittent Fasting & the Gut Microbiome
23:38 Fermented Foods, Microbial Diversity & Butyrate
27:12 H. pylori, Stress & Stomach Ulcers
30:20 GLP-1 Medications: Benefits & Limitations
33:42 Lower GLP-1 Doses, Weight Regain & Muscle Loss
37:35 GLP-1 Side Effects, Food Noise & Apathy
39:49 Bariatric Surgery & Medical Innovation
46:07 Sponsor: AG1
47:44 Hunger & Satiety: Ghrelin, CCK, GIP & GLP-1
50:01 Retatrutide & Combining Hormonal Targets
52:55 Ultra-Processed Foods, Overeating & Leptin
55:32 Incretin Discovery, Exendin-4 & the Gila Monster
59:35 Endoscopic Ultrasound & Pancreatic Biopsy
1:07:40 Early Metabolic Markers, CGMs & Fasting Insulin
1:13:06 Insulin Resistance & Metabolic Flexibility
1:15:53 Sponsor: Function
1:17:35 Patient Data, Screening & Treatment Adoption
1:26:31 AI, Robotics & Improving Procedures
1:29:27 Choosing a Surgeon & Measuring Procedure Quality
1:35:29 Image Guidance & Hyperspectral Imaging
1:37:19 Sponsor: Our Place
1:38:56 Diagnostics & Targeted Metabolic Treatments
1:42:45 Gastric Bypass, Foregut Exclusion & Diabetes
1:47:59 Duodenal Liners & Mucosal Resurfacing Research
1:52:58 Gut Permeability, Inflammation & Fatty Liver
1:59:39 Artificial Sweeteners, Fructose, Fats & Omega-3s
2:05:00 Resistance Training, Zone 2 Cardio & Intervals
2:06:31 Weight Set Point & Metabolic Adaptation
2:08:13 Endoscopic Sleeve Gastroplasty & Fundus Ablation
2:10:30 Magnetic Intestinal Connections & Combined Treatments
2:16:52 GLP-1 Gene Therapy Research
2:22:13 Innovation, Problem Solving & Teamwork
2:25:58 Zero-Cost Support, Sponsors & Neural Network Newsletter

Includes paid partnerships.

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Chris Thompson, MD @MetabolicEndo Sep 29

Congratulations!! We are all so proud to have been a part of your training @BrighamGI and are looking forward to the amazing things you will accomplish.

Thomas R McCarty @ThomasRMcCarty3 Sep 29

Honored and humbled to be selected. Big thank you to Elizabeth Blanton and Peter S Wareing! Could not have been possible without the unwavering support and leadership from @eamonnquigleymd! @HMethodistMD
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Chris Thompson, MD @MetabolicEndo Sep 25

Metabolic disease often begins with compensation, not failure.

Blood glucose can still look normal because insulin is working harder to keep it there.

The abnormality is not always the number you see. Sometimes it is the effort required to keep that number normal.

Chris Thompson, MD @MetabolicEndo Sep 21

Two people can have the same fasting glucose: 92 mg/dL.

One may need very little insulin to keep it there.
The other may need several times as much.

Glucose tells you the result.
Insulin tells you the cost.

That is how metabolic disease can remain hidden for years.

Chris Thompson, MD @MetabolicEndo Sep 21

Metabolic disease can start years before your A1C turns abnormal.

Insulin resistance may build quietly while glucose still looks “normal.”

In my new Forbes article, I lay out 6 measurable layers of metabolic disease, and how to detect them earlier.

Catch Metabolic Disease Years Before Your A1C Flags It via @forbes forbes.com/sites/christop…

www.forbes.com Catch Metabolic Disease Years Before Your A1C Flags It Obesity, type 2 diabetes, fatty liver and heart disease are usually recognized long after a silent process has begun.

Chris Thompson, MD

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