@MillerGroupYale
pubs.acs.org Further Confirmation of the Structure of 3′-(2-Pyridyldithio)-3′-deoxyadenosine and 3′-Thio-3′-de... Abstract. 3′-Deoxynucleosides have demonstrated profound biochemical utility, including in our recent work on the use of aminoacyl thio-tRNAs for in vitro 
pubs.acs.org Selective Oxidation of Disparate Functional Groups Mediated by a Common Aspartic Acid-Based Peptide... Conspectus. As drug molecules become increasingly complex, the need to develop new or improved strategies for the efficient and selective synthesis and edi 
pubs.acs.org Catalyst-Controlled Site-Selective and Epimer-Selective Hydrogenations of Thiostrepton Abstract. The hydrogenation of the antibiotic thiostrepton with control over the site- and stereoselectivity of reduction is reported. Studies on model sub 
pubs.acs.org Enantioselective Hydrodifluoroalkylation of Alkenes with Conformationally Tuned Peptidyl Hydrogen... Abstract. We report the enantioselective hydrodifluoroalkylation of alkenes proceeding via an asymmetric hydrogen atom transfer (HAT) event catalyzed by th 
pubs.acs.org Enantiocontrolled Cyclization to Form Chiral 7- and 8‑Membered Rings Unified by the Same Catalyst... Abstract. Chiral medium-sized rings, albeit displaying attractive properties for drug development, suffer from numerous synthetic challenges due to difficu 