Mingxia Gu

@MingxiaGu

Associate Professor @UCLA. #iPSC, #organoids, #vascular development, regeneration, and aging

Los Angeles, CA mgulab.org Joined September 2011

777 Following 1.1K Followers 312 Posts

Latest posts 5

Mingxia Gu @MingxiaGu Dec 29, 2025

Our study shows that hyperoxia drives lung endothelial cells into a non-regenerative state through isoform specific disruption of NTRK2, and that isoform-targeted correction restores vascular regeneration and enables disease modifying lung repair. Grateful to all contributors 🎉

Cell Stem Cell @CellStemCell Dec 24, 2025

Online Now! Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia dlvr.it/TQ0H2z #stemcells
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Mingxia Gu @MingxiaGu Jun 30, 2025

Excited to share our recent work on organoid vascularization, now out in @CellCellPress! Grateful to all our amazing collaborators who made this possible! @CuSTOM_CCHMC @UCLAstemcell

Darrell Kotton @Kottond Jun 30, 2025

Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! "Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids" cell.com/cell/fulltext/…
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Mingxia Gu @MingxiaGu May 16, 2025

Excited to share our latest study showing that restoring the balance between NTRK2 isoforms offers a promising therapeutic approach to promote pulmonary vascular regeneration! biorxiv.org/content/10.110…

www.biorxiv.org Isoform-Specific Roles of NTRK2 in Pulmonary Vascular Regeneration Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants with no curative therapy, characterized by impaired alveologenesis and capillary formation. However, the molecular...

Mingxia Gu @MingxiaGu Mar 20, 2025

Truly appreciate the opportunity to discuss the development of both lung microvasculature and academic careers—navigating challenges and opportunities in science and beyond! @ISSCR @UCLAstemcell

StemCellReports @stemcellreports Mar 20, 2025

The newest podcast is now live. Listen here tinyurl.com/ej429twb or wherever you download your favorite podcast. @ISSCR @paolo_panza @StainierLab @MingxiaGu @UCLAstemcell

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Mingxia Gu @MingxiaGu Nov 12, 2024

I also want to express my gratitude for the incredible support from Pulmonary Biology and @CuSTOMOrganoids over the past five years. It’s been a truly collaborative and nurturing environment—I’ll miss everyone and hope we stay connected!

Mingxia Gu @MingxiaGu Nov 12, 2024

Excited to share that our lab is moving to @UCLAstemcell @UCLAAnes in February 2025! While it's bittersweet to say goodbye to my wonderful colleagues and friends at CCHMC, I'm thrilled for the journey ahead as we dive into organoid engineering in Southern California! #firsttalk👇

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