Niels Fischer

@N__Fischer

Project group leader in structural biology @mpi_nat

Joined June 2021

191 Following 273 Followers 69 Posts

Latest posts 5

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Niels Fischer @N__Fischer Sep 20, 2024

How does the human #ribosome machinery select an open reading frame on mRNA for translation? Check out our #cryoEM work @NatureSMB: rdcu.be/dUbMg

Thanks to all involved - most of all first author @V_Petrychenko and our collaborators from the Rodnina lab @mpi_nat. 1/5

Niels Fischer @N__Fischer Sep 24, 2024

Ever wondered what else to do with your 3D printer? Here we used it to simulate #ribosome subunit joining in presence of the large eIF3 complex.

Read our full #cryoEM story on the human 48S translation initiation machinery @Naturesmb: doi.org/10.1038/s41594…

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Niels Fischer @N__Fischer Jan 30, 2024

Great work and movie on the structure and function of eIF4A and eIF4F in the human 48S translation initiation complex, congrats!

Jay Brito Querido @Jayquerido Jan 29, 2024

I am thrilled to share our new paper published in @NatureSMB (Brito Querido et al., 2024). #CryoEM structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
#Ribosome #mRNA #Science
nature.com/articles/s4159…

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Niels Fischer @N__Fischer Aug 21, 2023

#cryoDRGN joins #teamtomo - cryoDRGN-ET by @ZhongingAlong and co-workers: biorxiv.org/content/10.110…

www.biorxiv.org Deep reconstructing generative networks for visualizing dynamic biomolecules inside cells Advances in cryo-electron tomography (cryo-ET) have produced new opportunities to visualize the structures of dynamic macromolecular machinery in native cellular environments. Here, we describe a...

Niels Fischer @N__Fischer Aug 26, 2022

It has been really a pleasure to participate in the summer school of the @Tampe_Lab and give a talk on the human #ribosome & atomic-resolution #cryoEM. Big thanks to Robert Tampé, the whole Tampé lab, Anne Halenius & @BosnjakBerislav for great scientific tales and discussions!