Nace Mikus

@NaceMikus

Computational modelling in psychiatry and psychopharmacology § like going up and coming back down again § Bayesian

Joined November 2019

411 Following 136 Followers 38 Posts

Latest posts 3

Nace Mikus @NaceMikus Nov 28, 2023

New preprint: schizotypal traits and positive symptoms in (chronic & stable) patients are related to beliefs about volatility and not observational noise. (Glad that’s finally solved..)
medrxiv.org/content/10.110…
with @ClausLamm and @chmathys

www.medrxiv.org Computational phenotyping of aberrant belief updating in individuals with schizotypal traits and... Psychotic and psychotic-like experiences are thought to emerge from various patterns of disrupted belief updating. These include belief rigidity, overestimating the reliability of sensory informati...

Nace Mikus @NaceMikus Jul 11, 2023

Blocking D2 dopamine receptors increases the volatility of beliefs about other people.
nature.com/articles/s4146…

Work the late Chris Eisenegger (<3), and Michael Neaf started
and @ClausLamm , @chmathys and I finished
(w Trevor Robbins, @LukeClark01 and Ulrich Müller).

Nace Mikus @NaceMikus Dec 6, 2022

New paper out with @SilaniLab @chmathys in @eLife!

Does blocking opioid or dopamine D2 receptors increase model-based behaviour?

elifesciences.org/articles/79661

elifesciences.org Effects of dopamine D2/3 and opioid receptor antagonism on the trade-off between model-based and... Blocking D2 dopamine receptors increases goal-directed (“model-based”) control when alternative habitual ("model-free") actions are available, whereas blocking opioid receptors does not seem to have...