Practical Neurology

#Fenebrutinib was shown to reduce slowly expanding lesion accumulation in both relapsing #multiplesclerosis and primary progressive #MS in data presented at #MSToronto2026.
ow.ly/rHC55104K6e
@ACTRIMS @ECTRIMS @mssociety

#Vagus nerve stimulation was associated with sustained seizure reductions in people with drug-resistant #epilepsy in the prospective CORE-VNS study.

At 36 months, median seizure frequency decreased 76%, with fewer seizure-related hospitalizations and ED visits.
ow.ly/5w9T5104K3K
@AmEpilepsySoc @livanova

What options remain when highly active #tumefactive #MultipleSclerosis continues despite high-efficacy therapy?

Dr Waser, Dr Boggild, and Dr Wight report a case involving treatment escalation and the clinical course following autologous stem cell transplantation.
ow.ly/PwNe5104kj2
@mssociety #MS #Neuroimmunology #AHSCT @ACTRIMS @TownsvilleHHS

Subclinical optic nerve lesions were detected in nearly 60% of individuals with radiologically isolated syndrome (#RIS) but were not associated with clinical conversion to #MultipleSclerosis or MRI disease activity, according to findings presented at #MSToronto2026.
ow.ly/h1Tk5103WzR
@ACTRIMS @ECTRIMS @mssociety

Can #MultipleSclerosis be identified before a typical clinical attack?

A pilot study presented at #MSToronto2026 found that 67% of individuals meeting criteria for radiologically isolated syndrome or subclinical #MS had #MRI markers associated with an unfavorable prognosis.

ow.ly/HKGX5103ynY
@ACTRIMS @ECTRIMS @mssociety