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Ruggiero Norfo

@RuggieroNorfo

Researcher @UNIMORE_univ , Italy-
Interested in haematopoietic stem cell biology, myeloid neoplasms-
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Joined June 2023
304 Following 61 Followers 22 Posts

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Ruggiero Norfo @RuggieroNorfo
Excited to share this story about T cell exhaustion in myelofibrosis and how CTLA-4 blockade re-activates anti-tumour immunity in vitro and in vivo, now published in @AJHematology!🎯
Kudos to @LaraTavernari and #SebastianoRontauroli, within the @RM_Lab_!
onlinelibrary.wiley.com/doi/10.1002/aj…
onlinelibrary.wiley.com Targeting exhausted cytotoxic T cells through CTLA‐4 inhibition promotes elimination of neoplastic... Anti-CTLA-4 monoclonal antibody treatment dramatically decreased monocytes and granulocytes numbers in the BM of PDX mice.
Manfredini Lab @RM_Lab_ Jul 3, 2024
Congrats @LaraTavernari , @RuggieroNorfo , and @SebastianoRontauroli for leading this fantastic study on exhausted cytotoxic T cells rescue in #myelofibrosis xenografts! Out today, read it in @AjHematology 👉 doi.org/10.1002/ajh.27…
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Ruggiero Norfo @RuggieroNorfo
🔥🔥 Thrilled to share our latest work performed in close collaboration with the @RM_Lab_ and Vannucchi Lab. Amazing teamwork from all the people involved! Here we analyze how JAK2V617F and Chromosome 9p CNVs interact to modify disease phenotype in MPNs. See 🧵 below
Manfredini Lab @RM_Lab_ Aug 30, 2024
1/Excited to share our latest study on the effect of chromosome 9p duplication in JAK2-mutated Myeloproliferative Neoplasms - now out in
@LeukemiaJnl 🎉
nature.com/articles/s4137…
🧵below:
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