@SagarGupta047
Deciding which patients can receive #CAR T therapy is an important clinical question. By uncovering the structural basis of #MHC antigen recognition by a #neuroblastoma-targeting CAR we double the patient cohort and limit off-target toxicity @SciImmunology
science.org/doi/10.1126/sc…View quoted post on X
In collab w/ the Maris lab @CHOP_Research, we solve the #structure of the peptide-centric #CAR bound to #PHOX2B/HLA-A*24! The PC-CAR can recognize #HLAs from the A9 CREG (25.2% USA pop freq) and a specific peptide backbone is req’d for optimal recognition biorxiv.org/content/10.110…View quoted post on X
#HLA3DB: fast & reliable structure prediction of #MHC-I complexes. @SagarGupta047 @SANTRUPTI62
biorxiv.org/content/10.110…View quoted post on X
www.mdpi.com Role of Alternative Elicitor Transporters in the Onset of Plant Host Colonization by Streptomyces... Plant colonization by Streptomyces scabiei, the main cause of common scab disease on root and tuber crops, is triggered by cello-oligosaccharides, cellotriose being the most efficient elicitor. The... 
