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Sebastian Eves-van den Akker

@Seb_EvdA

Professor of Biotic Interactions, University of Cambridge. @plantsci Fellow of King's College Cambridge. goo.gl/fRtMjq
Cambridge, England sebastianevesvandenakker.com Joined May 2014
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Sebastian Eves-van den Akker @Seb_EvdA
Paper @PNASNews

We think nematodes break open plant cells, sense small molecules (termed effectostimulins), which switch on a master regulator SUGR1, which switches on effectors, which break cells.

Looks like a feed-forward loop driving infection.

pnas.org/doi/10.1073/pn…
www.pnas.org The SUbventral-Gland Regulator (SUGR-1) of nematode virulence | PNAS Pathogens must precisely tailor their gene expression to cause infection. However, a signaling cascade from host signal to effector production has ...
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Sebastian Eves-van den Akker @Seb_EvdA
Paper alert!

The host range paradox of Meloidogyne incognita.

Does an obligate biotroph with >2000 species host range "know" its on different plants?

Seems so (at least in terms of gene expression), but basically we don't understand what it knows.

@vmourade @camplantsci
The host range paradox of Meloidogyne incognita

Moura de Souza et al. @camplantsci @vmourade @Seb_EvdA

nph.onlinelibrary.wiley.com/doi/10.1111/np…
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Sebastian Eves-van den Akker @Seb_EvdA
During a trip to Iowa last month I sat down with Ed from the "I see dead plants" for a podcast. We mostly discuss work in the lab on 3D printing, AI, and phenotyping plant-nematode interactions.

A short, and links to the full podcast, below.
🪱🔬💻🎙️ New Podcast Episode!
What happens when cutting-edge technology meets one of agriculture's most important microscopic pests?
In this episode, we explore how researchers are using machine learning, artificial intelligence, advanced imaging, and even 3D printingto revolutionize the way we study plant-parasitic nematodes. From collecting better data to creating new tools for research, these technologies are helping scientists uncover insights that were once impossible to see.
Join us as we discuss the future of nematology and how innovation is transforming our understanding of these hidden threats beneath our feet.
🎧 Listen now:
Spotify: [open.spotify.com/episode/6JmRHL…]
Apple Podcasts: [podcasts.apple.com/us/podcast/s5-…]
YouTube: [youtube.com/@CropProtectio…]
#Nematology #PlantPathology #MachineLearning #ArtificialIntelligence #AgTech #3DPrinting #PlantScience #Agriculture #AgPodcast

@CropNetwork @ncipmc @Seb_EvdA @camplantsci
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Sebastian Eves-van den Akker @Seb_EvdA
Awesome work - congrats @AnikaDamm and the whole team!

The second master regulator of nematode effector expression - and it works antagonistically with the first!
Anika Damm @AnikaDamm Jun 15
Very excited to share our new preprint on DGR-1: a nematode master regulator controlling the switch from destructive to biotrophic effectors. We show that nematodes hijack the natural compartmentalisation of plant signals to fine-tune DGR-1 expression. biorxiv.org/content/10.648…
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