Sorek Lab

@SorekLab

The Sorek Lab

Israel weizmann.ac.il/molgen/Sorek/ Joined January 2015

268 Following 8.6K Followers 1.1K Posts

Latest posts 5

Sorek Lab @SorekLab Jan 31, 2025

Now published @ScienceMagazine: TIR signaling activates caspase-like immunity in bacteria

We report a new immune molecule: N7-cADPR. Produced by phage-induced TIRs and activates a defensive bacterial caspase

Congrats @FrancoisRousset & @IlyaOsterman!

science.org/doi/10.1126/sc…

Sorek Lab @SorekLab Jan 30, 2025

Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems

CARDs are essential for caspase recruitment in inflammasome activation. We now find them in bacterial immune systems

Congrats @TanaWein! Thanks Kranzusch lab!
tinyurl.com/CA88DD

Sorek Lab @SorekLab Jan 23, 2025

Our paper out @CellCellPress: Structure-guided discovery of viral proteins that inhibit host immunity

Congrats @ErezTzvi, Azita Leavitt, @amitai_gil, our collaborators @ Kranzusch lab, and coauthors

A 🧵 1/10

cell.com/cell/abstract/…

Sorek Lab @SorekLab Jan 23, 2025

Thank you @theNASciences 🙏

It is an immense honor to be included in the same list as the giants in microbiology who received the Selman A. Waksman Award

National Academy of Sciences @theNASciences Jan 23, 2025

We are honoring Rotem Sorek of @WeizmannScience with the 2025 Selman A. Waksman Award in Microbiology for groundbreaking discoveries on the immune system of bacteria. Congratulations! Learn about his research: nasonline.org/award/selman-a… #NASaward #microbiology

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Sorek Lab @SorekLab Dec 11, 2024

Evolutionary necessity for immune innovation harnessed components of the bacterial flagellar motor into a wild defense system - Zorya

One of the most intriguing and sophisticated bacterial defense systems out there

Congratulations Nicholas Taylor and colleagues!

Nicholas M. I. Taylor Lab @NMITaylorLab Dec 11, 2024

Very happy our paper on Zorya anti-phage defense system is now published in
@Nature! 🥳 Big congrats to first authors
@HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab
and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s4158…

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