We study the ancestral function of genomic structural variants deleted in the human lineage using single-cell CRISPRi in chimpanzee cells biorxiv.org/content/10.110…
TYLER FAIR
@TylerFair_
Scientist at @arcinstitute with Luke Gilbert & Virtual Cell Initiative
699 Following 171 Followers 14 Posts
Latest posts 3
We investigate cellular differences between humans and chimpanzees using CRISPRi-based genetic screens sciencedirect.com/science/articl…
A short review/opinion I wrote with @brainevodevo, "identifying large-effect mutations–should they exist–and defining the effect size distribution for a measurable phenotype are central challenges facing genetic studies of human evolution” sciencedirect.com/science/articl…