Cellular repair of DNA breaks enables editing of the human genome.View quoted post on X
Do human cells repair RNA breaks, and can we use it to edit transcriptomes?
Our work with @ANemudraia and @WiedenheftLab is now online in @ScienceMagazine!
#ScienceResearch
science.org/doi/10.1126/sc…
Wiedenheft Lab
@WiedenheftLab
News & views from Wiedenheft lab at Montana State University @montanastate | Account is managed by lab members.
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Interested in #CRISPR? Check out this postdoc opening @SantiagoFrangos lab!
📢I'm hiring a Postdoc to join me at Dept. of @PennBiology at @Penn! We'll use bioinformatics 🖥️, biochem 🧪, and cryo-EM ❄️🔬, to study how CRISPR systems work & applications. Work on cool science with a supportive mentor!View quoted post on X
Reposts appreciated!
Ringing in the new year with a pre-print on the PARIS defense system! This work defines how viral proteins activate PARIS-mediated tRNA cleavage and how viral tRNAs rescue infection. tinyurl.com/5x7epzxd. Also check out complementary work from the Corbett lab!
Check out this wonderful highlight of our very own @SantiagoFrangos! At the #BiomedicalBeat from @NIGMS and written by @abbeybigler!
More exciting #CRISPR research from the lab! Check out the thread by @SantiagoFrangos 👇🏽
Vertebrates, bacteria, and archaea have domesticated transposases for adaptive immunity. Transposases often get help from other DNA-bending proteins. But what’s the role of DNA bending in the cutting and pasting of DNA? biorxiv.org/content/10.110… (1/16)View quoted post on X