Alan Brown

@alanbrownhms

Structural biologist studying cilia and ciliopathies.

Boston, MA brown.hms.harvard.edu Joined May 2014

415 Following 1.7K Followers 293 Posts

Latest posts 5

One, perhaps two, of our postdocs are moving on to faculty positions this year (more news soon!). While they're truly irreplaceable, it does mean that we have openings for new members to join our team studying #cilia. If interested, please apply: academicpositions.harvard.edu/postings/15526

Alan Brown @alanbrownhms Mar 28, 2024

The mastigoneme, a little-known hair on algal cilia, contains some fascinating biology. Our latest work with @RuiZhangWUSTL reveals insights into the hydroxyproline glycosylation code, filament length control, and the coupling of filaments to ion channels cell.com/cell/fulltext/…

www.cell.com Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyprol... Structure of the native C. reinhardtii mastigoneme allows visualization of the glycan patterns associated with different types of proline repetition in two different hydroxyproline-rich glycoprotei...

Alan Brown @alanbrownhms Jun 15, 2023

Fabulous start to your new lab! I expect there's a lot more cases of MIP-variant-associated asthenozoospermia to be discovered

Miao Gui @miao_gui Jun 15, 2023

Thrilled to share my FIRST corresponding author paper as #newPI @CellCellPress. We looked at the structures of sperm flagellar doublet microtubules (DMTs) and defined a new subtype of male infertility. #cilia #maleinfertility authors.elsevier.com/c/1hDJeL7PXmcfd
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Alan Brown @alanbrownhms Jun 15, 2023

This was a great collaboration to be a part of. Sperm doublets are wild!

Tzviya Zeev-Ben-Mordehai @TzviyaZBM Jun 15, 2023

I am thrilled our results on sperm axonemal doublet #microtubules are now out in Cell. Outstanding work of Miguel Leung and amazing collaboration with @RuiZhangWUSTL and @alanbrownhms
cell.com/cell/fulltext/…

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Alan Brown @alanbrownhms May 1, 2023

I couldn't be prouder. Miao was a PI's dream and will make a dream PI. Expect big things from his lab in the coming years.

Miao Gui @miao_gui Apr 28, 2023

I have started my own research group at Zhejiang University in Hangzhou, China. I'm truly grateful to @alanbrownhms for supporting me in the last few years. Thank my wonderful colleagues and collaborators especially @RuiZhangWUSTL.
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