Miao Gui

@miao_gui

Cilia, cryo-EM and more. PI @ZJU_china. Former member of Brown lab @harvardmed.

Hangzhou miaoguilab.com Joined January 2018

596 Following 641 Followers 249 Posts

Latest posts 5

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Miao Gui @miao_gui Jun 1, 2023

I’m delighted to share our work @alanbrownhms on the structures of axoneme, one of the largest macromolecular machine in nature! This is really a dream coming true! Now we have an atomic view of the core of cilia skeleton. nature.com/articles/s4158…

Miao Gui @miao_gui Jul 2, 2025

Happy to contribute to this fascinating story!

Qiang Guo @QiangGuo_EM Jul 1, 2025

Our Basal Body Story is Now Online!
It’s been a long journey. Initially, we plan to understand how the basal body assembles, but along the way, we stumbled upon an unexpected opportunity to explore biogenesis as well.nature.com/articles/s4146…
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Miao Gui @miao_gui Jun 23, 2023

A preview of our recent paper on sperm DMT👇

Yoshi__ichikawa @Yoshi__Ichikawa Jun 22, 2023

We wrote a Preview paper “Tektin makes a microtubule a ‘micropillar’” in Cell @CellCellPress for two amazing papers of doublet microtubule structures from sperm flagella published by Leung et al. and Zhou et al.
authors.elsevier.com/a/1hIEbL7PXmcgg
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Miao Gui @miao_gui Jun 15, 2023

Thrilled to share my FIRST corresponding author paper as #newPI @CellCellPress. We looked at the structures of sperm flagellar doublet microtubules (DMTs) and defined a new subtype of male infertility. #cilia #maleinfertility authors.elsevier.com/c/1hDJeL7PXmcfd

Miao Gui @miao_gui Jun 11, 2023

Beautiful work. You are continuously pushing the boundary of cryo-ET

Liang Xue @Liang_Xue_ Jun 9, 2023

Glad to share our new cryo-ET work
biorxiv.org/content/10.110…
I resolved ribosomes to sub-3 Å in cells, realizing the potential we demonstrated. In PTC core where our interested drug Chloramphenicol binds, the local res. hit 2.7 Å, enabling deciphering its MOAs in atomic details.

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