Chaolin Zhang

@chaolinzhang

Prof @Columbia Univ | RNA-Protein Interaction, Neuronal Alternative Splicing, RNA-based Medicine | prev. @RockefellerUniv @CSHL @Tsinghua_Unv | 📢 hiring now

Columbia University, New York, NY zhanglab.c2b2.columbia.edu Joined December 2016

565 Following 2.4K Followers 1.8K Posts

Latest posts 5

Chaolin Zhang @chaolinzhang 2d

Glad to see the new splicing prediction models from sequences that are conditioned on cellular conditions (as represented by expression of splicing factors), including #SpliceAI2, #AlphaGenome2 and a few others.

Congrats @kjaganatha, @adamgayoso, @Avsecz and teams! Looking forward to digesting more details and understanding where we stand!

biorxiv.org/content/10.648…
deepmind.google/blog/alphageno…

www.biorxiv.org A unified framework for quantitative splicing and transcript prediction RNA splicing is frequently disrupted by genetic variation, contributing to a wide range of human diseases. Identifying the variants responsible for altered splicing is therefore crucial but has long...

Chaolin Zhang @chaolinzhang Nov 5

Glad to be able to contribute a small part with Shah Alam and Wangyang Dai in the lab!

Xuebing Wu @wu_xuebing Nov 4

Excited to share that our MYC mutagenesis paper is now online at @CellCellPress! Free access link through Dec 24 authors.elsevier.com/a/1o316L7PXy4lc. Special thanks to our handling editor Jude @JudeNicho and the reviewers for their support and feedback throughout the process!

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Chaolin Zhang @chaolinzhang Oct 1

"If the human brain were so simple that we could understand it, we would be so simple that we couldn't." - Emerson M. Pugh (1938)

Chaolin Zhang @chaolinzhang Sep 30

Thrilled to be one of the 25 winners for the @NIH #TRDNT Challenge (Phase 1). 🏆 🏆🏆We will develop an all-in-one #RNA trans-splicing platform for highly efficient and programmable exon editing. We hope to expand the list of druggable target genes that are challenging with current technologies.

Kudos to the leading postdoc in the lab Ye Wang for what we have achieved so far! I am very excited about what to expect moving forward!

@ColumbiaSysBio
@ColumbiaPS
@Columbia

#RNA
#PrecisionMedicine

nih.gov/challenges/tar…

www.nih.gov Targeting RNA in Disease with Novel Technologies (TRDNT) Challenge [Enter summary here]

Chaolin Zhang @chaolinzhang Aug 11

🔥🔥🔥The deadline for abstract submission has been extended to August 28. We still have some spots for short talks (and posters) and look forward to having you join us in Suzhou if you are interested in frontiers of genome biology from either computational or experimental side!
👉 csh-asia.org/?content/3096

Chaolin Zhang @chaolinzhang Jul 21

Excited to announce the Cold Spring Harbor Asia Conference on Genome Biology: Computation, Technology, and Discovery (Oct. 12–16, Suzhou, China)!

I’m delighted to co-organize this meeting again with @cdessimoz, Jing-Dong Jackie Han, and @jmuiuc. We’ll bring together an outstanding group of researchers spanning genomics, AI, computation, and cutting-edge technology development to the beautiful garden city 30 min from Shanghai by high-speed train.

📅 Abstract deadline: Aug. 7 (just over 2 weeks away)

Please RT!

csh-asia.org/?content/3096

@CSHANews

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