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Excited to share our latest work. We developed a modified TraDIS appropriate for host cell infections where bacterial yields are limiting and applied it to a stage-resolved human bladder culture model of UTI @AIMI_UTS
journals.asm.org/doi/full/10.11…
journals.asm.org Genetic requirements for uropathogenic E. coli proliferation in the bladder cell infection cycle |... Urinary tract infections (UTIs) are one of the most frequent infections worldwide. Uropathogenic Escherichia coli (UPEC), which accounts for ~80% of UTIs, must rapidly adapt to highly variable host... journals.asm.org/doi/full/10.11…