Jai Tree

We're hiring!

A post-doc position is available in the lab to work on RNA-based virulence gene regulation in bacteria.

Come and join us in Sydney, Australia 🐨

Email details, and please RT.

external-careers.jobs.unsw.edu.au/cw/en/job/5202…

Our work on the RNA interactome of Staph is out (twice!). Using RNase III-CLASH our groups uncovered RNA interactions controlling vancomycin tolerance (a last-line antibiotic) and production of cytolytic toxins.
nature.com/articles/s4146…
nature.com/articles/s4146…

Surprisingly literal interpretation of our manuscript title by AI artwork wombo.art - “Burning the Candle at Both Ends: Have Exoribonucleases Driven Divergence of Regulatory RNA Mechanisms in Bacteria?” doi.org/10.1128/mBio.0…

Lovely work from the Olejniczak lab on how small RNA sponges position themselves on Hfq for interactions with fellow sRNAs. @EMaleckaPhD doi.org/10.1016/j.jmb.…

Regulatory RNAs seem to be quite different in Gram + and Gram - bacteria. During lockdown, @danmed and I started discussing some ideas with @DavidLalaouna. We propose that 5’-3’ exoRNase may be a barrier to 3’UTR sRNA evo and that restricts expansion of Hfq and ProQ function👇