deWitLab

You may know ZNF143 as a looping factor. We show together with the @hansen_lab that this is not the case! If you want to know why and what it does instead do read our thread below:
biorxiv.org/content/10.110…

Check out our COGEDE review on loops in the 3D genome. We describe how genomic regions are brought together, i.e. loop extrusion, compartmentalization and protein-protein interactions and how these processes influence each other. With @MMagnitov

sciencedirect.com/science/articl…

We have an open post-doc position in the lab. If you're interested in studying the role of the cohesin complex in gene regulation, don't hesitate to apply. Come and join us in beautiful Amsterdam! Email me if you have specific questions. nki.nl/careers-study/…

Note that you can register for NWO Life: nwolife.nl 22-23 May!

Our paper on patient-specific MYC enhancers in malignant rhabdoid tumors was just published in @NatureComms Please the link here: nature.com/articles/s4146…
Excited to see our fundamental research on 3D genome folding help to understand this highly aggresive and deadly disease.