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Derek Alia

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@derekalia

Wizarding @muni_bio
San Francisco, CA Joined December 2008
1.1K Following 1.3K Followers 907 Posts

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Derek Alia Verified account @derekalia
The factorioization of biology is happening.

Expect faster/cheaper experimental validation and more novel drugs developed at a fraction of todays cost.

My sense is that many people inside the drug development industry are further behind in understanding what's becoming possible than those on the outside looking in. Which leads to an interesting arbitrage, bound purely by ambition.

Teams that embrace agentic workflows will soon look like an entirely different species of biotech, one that the old guard will struggle to comprehend.

Some will interpret this negatively as the removal of human creativity from biological research, my view is opposite. I think this gives people with deep biological insight far more leverage. Freeing them from the tedious, repetitive work that consumes most of their context.

Exciting times.
Kat Verified account @katyenko Oct 30
Binding is nice, but it’s getting boring. If you’re not thinking about biological function, you’re ngmi.

At our last @muni_bio hackathon co-hosted with @onepot_ai, we set one ambitious goal: neutralize the latest threat of Ebola using small molecules.

The wet lab data is in, and we’re excited to announce that teams were successful, including our agent that repurposed... an anti-itch gel?

muni.bio/research/hits-…
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Derek Alia Verified account @derekalia
new funding path unlocked. who needs vc when you can have the public foot the bill via taxes?!?

this is crazy.
immad Verified account @immad 4d
Something feels a bit iffy about California prop 38.

Doing a popular vote proposed by a 3 person non-profit that gives said non profit $4.2B from the public!

I hope Gary is great and knows how to spend $4.2B well because it’s done.
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Derek Alia Verified account @derekalia
Lets go!!! I've been waiting for something like this.
Chenru Duan Verified account @chenru_duan 6d
We’re introducing Hydrogen-1.0, our first open-weight model for scientific research. We post-trained GLM-5.3 (@Zai_org) on our internal scientific data, lab records, and discovery trajectories.

It scores 38.3% on FrontierScience-Research vs GPT-6-Astra’s 33.3% and scores 93.0% on GPQA-Diamonds.

We believe science should be open, collaborative, and democratized, rather than proprietary. Only open weights let researchers inspect, adapt and build on the unprecedented speed of AI growth. There are many recent models named by chemical elements, but we believe Hydrogen-1.0 is the first aiming towards and open scientific superintelligence for discovery. 🧵
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