Edward Larkin

Rohan Pavuluri Verified account @RPavuluri · 2d

A couple months ago, I started looking for great biotech podcasts that would help me learn from folks at the frontier of AI x Bio, both founders building companies and investors funding them.

Basically a @HarryStebbings @20vcFund, @MollySOShea @sourceryy, or @patrick_oshag @InvestLikeBest for biotech.

There were some great episodes but I couldn’t find a media platform that was exactly what I was looking for.

At the same time, I had the observation that biotech/pharma has the highest imbalance between how important the industry is to the world and how much storytelling the industry does around the people behind it.

These are some of the largest businesses in the world (so many $100B+ co’s) and there’s nothing more important to me than the medicines we make to cure disease in society. But the majority of stories are untold. And the majority of important people are widely unknown. Contrast this with the tech or financial services industry.

Fortunately, my wife @DeeyaKotecha practiced medicine before moving into biotech investing at Avoro Capital, one of the larger public market biotech specialist funds.

She was just as excited about this problem as I was and, given her passion for biotech and storytelling, decided to start The New Alchemist, a media platform focused on telling the stories of founders, operators, and investors on the frontier of AI x Bio.

We also thought it’d be fun to work on it together, though it’s 99% her and I’m just excited to learn.

I think a lot of tech/AI people are now looking towards bio as a way to channel their energy so I’m hopeful The New Alchemist can help inspire them! And we can play a small part in helping the wider public understand what goes into building the medicines they consume everyday.

@ealarkin7, founder of @Valius_Sciences epitomizes the AI-native founder of tmrw. He dropped out of med school to lead healthcare deployments at @PalantirTech & then led biotech & healthcare at Dragoneer.

He met @gitlab founder @sytses who pioneered much of the current discourse on maximal diagnostics in cancer and started Valius to give any patient the ability to be maximally diagnostic in overcoming their own cancer.

Edward is building a generational company and the perfect person to build it given his life path. Lucky for him to be our first guest.

If you have advice on people to interview or are also passionate about this mission, please reach out 🙏🏽💊

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Frank Gao Verified account @ChemVagabond · Oct 19

research.dimensioncap.com/p/six-nanomete…

The breakthroughs came from understanding HER2’s abundance, specificity and protein neighborhoods, alongside the biodistribution and internalization of drug candidates.

Over the last decade, tools for mapping cell surfaces and tracking molecules have become more powerful and more widely available.

In Dimension’s latest research article, “Six Nanometers Apart,” I explore how we can harness these emerging capabilities to repeat HER2’s success at scale and with much greater speed.

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JJ Maxwell @jjmaxwell4 · Oct 14

Things to know if you get Cancer (2026 Edition)

- I was diagnosed with Squamous cell carcinoma in my mouth in May 2026, here are some things I learned based on that experience so far.
- You need to be doggedly persistent on scheduling things. Yes this means lots of phone calls. If you get an appointment a few weeks out, call back a few days later and ask for something sooner and see if they have any cancellations. I could only get a appt 4 weeks out with an ENT (this was before I knew anything was wrong). My wife made me call back and I was able to get in that week due to a cancellation.
- AI’s may downplay the seriousness of things. I was chatting with various models and most pushed me in the direction of “you don’t have cancer” for a while. Just something to note.
- You may need to push for comprehensive genetic testing. Some doctors were weird about this and didn’t order it promptly, even after telling me they would. My surgeon who told me he’d get it done, eventually referred me out to an oncologist. This caused a multi-month delay to getting genetic results since the first results were done on the surgery tumor not the biopsy tumor. No one cares more about your case than you, so take control and send lots of follow ups!
- You can find the “Standard of Care” flow charts for every cancer type. Look and get through this yourself to see what the options are based on how things have progressed. nccn.org/guidelines/cat…. You may need to make an account which you can do as a non professional. I like the .pdf files, they also have a interactive navigator. Use AI to help you figure out what to pick based on your case.
- If surgery is recommended, I would try and talk to someone who has undergone the surgery. I did not do this and regret it. Ask them how intense things were, what it felt like etc. My surgeon talked me through my surgery but it was A LOT rougher on me physically than I expected. Ask the surgeon how many of these surgeries they do a year and what the complication rate is.
- Get a 2nd opinion as soon as possible. No matter how much you like your plan. This may require a lot of calling and getting on a airplane, but I’d move to schedule it at a top cancer center as soon as you are relatively sure of your diagnosis. Ask for a second read of the pathology at the center where you get the second opinion.
- I started a new folder on my Mac and after appointments I’d dictate what happened and what the doctor said and have the AI make a new document summarizing things and asking it’s own follow up questions for next time. Its nice to be able to refer to this over time. Can also download all your pathology, scans so they can be referenced.
- Checkout all the resources and materials at sijbrandijfoundation.org/fcct. @sytses (GitLab cofounder) took matters into his own hands when standard of care ran out. Schedule a call with these guys they are great and have good materials and questions to ask your doctors, etc

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