Gavin Knott

Excited to share our new paper describing the structure of an SpCas9 adenosine base editor (ABE) out now @ScienceMagazine! Co-first authored with @Sarkele1, we captured a base-editor in the act using cryo-EM! science.sciencemag.org/content/369/65… (1/5).

We are excited to share pre-prints describing a successful foray into ML-driven protein design. With @Rhys__G we designed proteins to potently inhibit CRISPR-Cas13 (doi.org/10.1101/2024.1…) or block heme piracy by pathogenic E. coli (doi.org/10.1101/2024.1…):

An amazing opportunity to work with an incredible team on cutting-edge CRISPR research. Would highly recommend working with Audrey and her team at ASU!

🚨We are hiring!🚨

The Knott Lab is looking for a Postdoctoral Fellow with experience in #CryoEM. Join us and be part of a global and industry aligned team of researchers studying #CRISPR and #RNA.

Details and how to apply: careersaustralia.monash.edu/cw/en/job/6404…

It’s been ~10 yrs since #CRISPR biotech exploded onto the scene. What’s new in the field and where is it headed? Join us in Berkeley for the 5th International Conference on CRISPR biotechnology to hear answers to these questions and more! More details - aiche.org/crispr