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Prof.Grant Schofield

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@grantsnz

Grant Schofield | Professor of Public Health | Chief Science Officer at PREKURE | Bestselling Author (4x) | Former Public Health Advisor | Leading the Movement
Auckland New Zealand profgrantschofield.com Joined June 2010
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Prof.Grant Schofield Verified account @grantsnz
New implant uses electrical signal to remove glucose from the blood.....I wonder if anyone thought of just not eating glucose in the first place?

"Diabetes and obesity are becoming increasingly common around the world, and they frequently coexist and reinforce each other. A variety of pharmacological and biological interventions are already available, but each has its advantages and disadvantages and many patients are still in need of better tolerated, more effective, and/or more affordable treatment options. An implantable device developed by Maity et al. helps to fill this gap by providing a controllable way to adjust blood glucose concentration without medications or insulin (see the Perspective by Bentley and Payne). The wirelessly powered device can be linked to a clinically available continuous glucose monitor to catalyze the conversion of glucose to gluconate, which is then renally excreted. This normalized blood glucose and simultaneously removed some of the excess caloric load when tested in mice. —Yevgeniya Nusinovich"

science.org/doi/10.1126/sc…
www.science.org Wireless electrocatalytic closed-loop system for drug-free management of diabesity Lifestyle-related type 2 diabetes and associated obesity (diabesity) affect >2.5 billion people worldwide and impose nearly $3 trillion in annual health care costs. We developed an implantable,...
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Prof.Grant Schofield Verified account @grantsnz
I wonder if anyone thought of not eating the glucose in the first place?
Smart Science Verified account @SmartScience Oct 29
🚨 This could be the end of Type 2 diabetes.

Researchers at ETH Zurich led by Martin Fussenegger built a small wireless implant that uses electricity to break down extra sugar in the blood.

It switches off when levels are normal — and means people won’t need diabetes drugs anymore.

Inside is a catalyst made of graphite felt coated with tiny gold and platinum particles, with no living cells or drugs. A glucose sensor worn on the arm watches sugar levels. When they climb after a meal, it signals a phone or smartwatch, which switches on the implant.

The catalyst then turns glucose into gluconate, a harmless compound the body flushes out in urine, and the system shuts off once sugar is back on target.

In diabetic mice, the device kept blood sugar under tight control for six weeks, the animals lost weight, and it caused no sign of tissue damage.

Because less sugar ends up stored as fat, the team sees it as a possible tool for both type 2 diabetes and obesity, without daily pills or injections. So far it has only been tested in mice, and human trials are still ahead.

source: Maity, D., et al. (2026). Wireless electrocatalytic closed-loop system for drug-free management of diabesity. Science.
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Prof.Grant Schofield Verified account @grantsnz
Get you HDL up - exercise more, eat les carbs and more fat.....
Dr. David Ludwig @davidludwigmd Oct 27
Is high LDL cholesterol (or apoB) harmful ONLY with poor metabolic health, characterized by low HDLc?

New study from preeminent lipidologist Sniderman:

"when HDL-C is high ... effect of changing apoB vanishes"

PS: A low-carb diet potently increases HDLc
academic.oup.com/eurjpc/advance…
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Prof.Grant Schofield Verified account @grantsnz
Fair point, get metabolically flexible produce less CO2
Alan Couzens Verified account @Alan_Couzens Oct 27
This is fascinating.

Human *metabolic* CO2 production almost doubled over the last 30 years.

60% is attributable to population growth, but the other 40% might be the most interesting.

Humans getting a lot bigger and fatter certainly comes into play, but metabolic health likely does as well.

Recall...

CO2 produced = TEE x RQ / EE of O2.

That is, as RQ (Share of energy coming from carbohydrate) goes up, like an inefficient factory spewing noxious gas into the atmosphere, your CO2 production also goes up! 🏭

So, for the sake of the planet 🌎...

Stop being a fatass. Get your metabolic health in order.
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Prof.Grant Schofield Verified account @grantsnz
I've been reading a lot of research for a lot of decades, and this has to top all study designs ever.

107 married couples. 21 nights. Finger-prick glucose before bed. Then each person, alone, sticks 0 to 51 pins into a voodoo doll that represents their spouse, depending how angry they are. Later in the lab they get to blast "their spouse" with loud noise through headphones (up to fire-alarm levels) and choose how long it lasts.

The lower the evening glucose, the more pins in the doll. And the people with lower average glucose turned the noise up louder and longer.

Is this the big problem of the sugar crash...ie, reactive hypoglycaemia?

Bushman et al., PNAS 2014
pnas.org/doi