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Ken Hallows

@hallowsk

Joined February 2009
29 Following 34 Followers 33 Posts

Latest posts 5

Ken Hallows @hallowsk
Association of Longitudinal Urinary Metabolic Biomarkers With ADPKD Severity and Response to Metformin in TAME-PKD Clinical Trial Participants kireports.org/article/S2468-…
www.kireports.org Association of Longitudinal Urinary Metabolic Biomarkers With ADPKD Severity and Response to... Dysregulated cellular metabolism contributes to autosomal dominant polycystic kidney disease (ADPKD) pathogenesis. The Trial of Administration of Metformin in Polycystic Kidney Disease (TAME-PKD)...
Ken Hallows @hallowsk
Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice pubmed.ncbi.nlm.nih.gov/36504724/
pubmed.ncbi.nlm.nih.gov Beneficial effects of bempedoic acid treatment in polycystic kidney disease cells and mice - PubMed ADPKD has few therapeutic options. Tolvaptan slows disease but has side effects limiting its tolerability. Bempedoic acid (BA), an ATP citrate-lyase (ACLY) inhibitor FDA-approved for hypercholester...