@kinasekid
Pinned post
Thrilled to share my freshly "baked" Baker lab paper. We took a bottom-up approach to designing transcriptional regulators. Instead of relying on natural activation domains, we designed compact proteins that recruit specific cofactors. Activators for now, repressors to come!View quoted post on X
www.science.org De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiple... Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: Proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabi... 💭How can AI help scientists study specific molecules in the crowded world of a cell?
Steffen Klein, together with the Baker Lab, used AI to design NovoTags, a new protein tag, helping scientists identify specific proteins inside cells via fluorescence microscopy.
#EMBL_AIView quoted post on X
@ArashVahdat @karsten_kreis @tomasgeffner @nscorley @RafiBrent @maxkazman @osclsd @nmboffi @ChoYehlin @jBonzaniniSci @noramcb The unified latent space pushes specificity further: with @kinasekid we bind phosphorylated serines and threonines specifically, and even site-selectively when they sit directly next to each other on a target! 22/30View quoted post on X
My little Blender plugin I started 4.5 years ago is literally the face of an entire Biotech industry / research sector 🥹View quoted post on X
#b3d #GeometryNodes #MolecularNodes
