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Daniel Michelson

@michelson_da

MD/PhD student @harvardmed @mit, studying T cell tolerance and what happens when it fails
Boston, MA dmichelson.com Joined November 2018
279 Following 382 Followers 137 Posts

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Daniel Michelson @michelson_da
Glad to share our latest thoughts on thymic mimetic cells, situating them within wider currents of molecular, cell, developmental and evolutionary biology:
doi.org/10.1146/annure…
Thanks @AnnualReviews @REMLehmann for the chance to contribute to a diverse and fascinating volume!
www.annualreviews.org Thymic Mimetic Cells: Ontogeny as Immunology Medullary thymic epithelial cells (mTECs) generate immunological self-tolerance by ectopically expressing peripheral-tissue antigens (PTAs) within the thymus to preview the peripheral self to...
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Daniel Michelson @michelson_da
Poison exons and gating of TCR signaling — such a cool connection from @takarginov between the bleeding edge of molecular biology and immunology!
The latter part of my thesis work on RNA binding proteins and T cells is out in @ScienceMagazine ! Here we find that one of the most conserved elements in the genome helps determine how your immune system responds to pathogens. #ScienceResearch
science.org/doi/10.1126/sc…
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Daniel Michelson @michelson_da
Check out this illuminating💡⚡️work from @kaitavjeet on the genomic wiring of Tregs! Some amazing insights including the fact that not all Tregs need FoxP3🤯🤯
Great to see this now out @PNASNews pnas.org/doi/10.1073/pn… Now with expanded analyses of FoxP3's contributions to Treg identity and of FoxP3-independent RORg+ Tregs. Grateful to mentors and collaborators for their support and contributions throughout this project!
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