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Michael VanInsberghe

@mvanins

Single-cell methods in translation and post-transcriptional regulation. Postdoc @_Hubrecht with @AlexandervanOu1 🇳🇱. PhD @ubcmsl with Carl Hansen 🇨🇦
Utrecht, NL Joined October 2012
207 Following 198 Followers 108 Posts

Latest posts 5

Michael VanInsberghe @mvanins
Several new technologies have enabled translation profiling in single cells. In our article in @NatRevMCB, @AlexandervanOu1 and I discuss these single-cell methods for measuring ribosome profiles, ribosome-associated transcripts, and spatial translation 🧵 nature.com/articles/s4158…
www.nature.com Sequencing technologies to measure translation in single cells Nature Reviews Molecular Cell Biology - Recent sequencing-based methods, including novel ribosome profiling, ribosome affinity purification and spatial translation methods, have enabled the...
Michael VanInsberghe @mvanins
Check out the final version of @jervdberg and @BVincentv's manuscript! I guarantee this won't be the last time you hear about scEdU-seq 🚀
Jeroen van den Berg @jervdberg Jun 17, 2024
Very happy our scEdU-seq manuscript is published in @naturemethods! Big shoutout to @BVincentv, @AlexandervanOu1 @marcelvanvugt, @Acebron and @Anchel_91 for their contribution to the final product! For those interested here is the link to the paper rdcu.be/dK2hL
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Michael VanInsberghe @mvanins
@dvaninsberghe Pretty surprising that this wasn’t the fir-st tree genome
PNASNews @PNASNews Jun 7, 2024
Researchers report the genome of the London plane, a common urban tree. The London plane has 42 chromosomes, resulting from two whole-genome doubling events, which led to gene functionalization changes and a two-year flowering period. In PNAS: ow.ly/nfRv50SaVeW
Genomic features of the representative pseudohaploid genome of P. × acerifolia. The circle layers from outer to inner represent: Each wedge represents a chromosome, the length of wedge indicates the chromosome size (Mb), and each group of 3 wedges of the same color represents 3 ancestral homeologs.
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Michael VanInsberghe @mvanins
Amazing work from @jervdberg and @BVincentv! Super cool to see how the project evolved and this unstoppable team pulled this together!
Jeroen van den Berg @jervdberg Dec 16, 2022
Exhilarated to share our pre-print describing a novel method, scEdU-seq, to measure DNA replication forks and their speeds in singe cells. Many thanks to @AlexandervanOu1, @Bvincentv and others @_Hubrecht for making it happen!
biorxiv.org/content/10.110…
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