Rodrigo Aguilar

@ragmau

👨🏻‍🔬 Profesor Investigador @IBiomedicas @uandresbello
🧬 Biología molecular, bioquímica, epigenética, ARNs no codificantes

Santiago, Chile rnaanddisease.com Joined August 2013

537 Following 477 Followers 1.6K Posts

Latest posts 5

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Rodrigo Aguilar @ragmau Aug 25

Hot off the press! Proud to share our latest paper about the important 3' end of MALAT1, a famous cancer-related lncRNA. Using CRISPR, we deleted several nucleotides across the gene, assessing its impact over RNA stability, structure, locus-related (1/n)

sciencedirect.com/science/articl…

Rodrigo Aguilar @ragmau Sep 23

Nuestro reciente trabajo fue explicado en @latercera . Les invitamos a leer aca 👇🏻

latercera.com/tendencias/not…

@fjbustosf @robertomunita @IBiomedicas

www.latercera.com Científicos chilenos descubren cómo desarmar un ARN clave en células tumorales de estómago y mama -... Los investigadores sostienen que sus resultados, obtenidos en modelos de laboratorio, podrían tener proyección hacia el desarrollo de futuros tratamientos contra el cáncer gástrico y de mama.

Rodrigo Aguilar @ragmau Mar 23

New RNA paper alert! 🧬🏗️

Using SAXS, 3D modeling, and RNA probing, we’ve mapped the B2 SINE RNA. We show how its dynamic tertiary structure directly dictates its ability to shut down transcription during stress.

Read more 👇🏻 nature.com/articles/s4200…

@XistHarvard @trushar_7

Rodrigo Aguilar @ragmau Dec 26, 2025

Excited to share our latest preprint on @bioRxiv! 🧬

With @AlvaroElorza, @gnardo, we investigated the lncRNA MALAT1 in thyroid cancer from Chilean patients and found it’s a key player in metabolic reprogramming and aggressiveness

Read more here: biorxiv.org/content/10.648…

www.biorxiv.org Increased MALAT1 Levels in Thyroid Cancer are Linked to Metabolic Reprogramming and Lymphatic... Metastasis-associated lung adenocarcinoma transcript 1 ( MALAT1 ) is a long non-coding RNA (lncRNA) implicated in cancer progression. In thyroid cancer, MALAT1 has been proposed as a potential...

Rodrigo Aguilar @ragmau Aug 25, 2025

Felicitaciones a l@s seleccionados del Endowment 2025 @uandresbello ! En especial a Marcelo Muñoz, graduado de nuestro laboratorio en 2024. Mucho éxito!