Slow Ventures

TJ Parker⚡️ Verified account @tjparker · Oct 6

General Medicine has raised a $120M Series B led by @a16z. We're using it to build the healthcare store.

The only way healthcare will work is to make the customer the most powerful participant in the system. And the only way to do that is to let them shop.

Here’s why healthcare needs a store, and what we had to build to make it possible:

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Harry Stebbings Verified account @HarryStebbings · Sep 7

The hottest category in tech right now is AI assistants.

The question is; who is going to win?

Instinct raised at $2.5BN. Has Benchmark and Index behind them.

Grok Bot is ripping with Elon and has the distribution machine of X.

And then there is Town, one of the only ones that’s actually making real money from real businesses.

Don’t write Zuck off. This will be his next play and integrated into every WhatsApp user’s product.

I sat down with Town Founder, @jgreze to understand WTF is going on, who wins and who loses?

Condensed my notes below!

1. We Have Passed the Point Where Humans Look at Lines of Code

Software engineering has crossed a threshold where machines increasingly write and ship code into production under model-based guardrails. Outside critical security controls, humans will spend far less time reviewing raw code. The future belongs to systems that manage autonomous AI agents writing software, running tests, and validating their own work.

2. You Can Build at the Speed of Machines, but You Can Only Learn at the Speed of Humans

AI development tools allow competitors to clone features in weeks, erasing traditional software head starts. But deep user feedback cannot be automated. While machines accelerate execution, true competitive advantage comes from maximizing human learning cycles and understanding customers faster than anyone else.

3. Why None of the AI Assistants Have True Product-Market Fit Today

Despite immense market hype, no current AI assistant has achieved deep product-market fit with mainstream users. Most products still cater primarily to power users rather than everyday workers. Before worrying about moats, founders need to create frictionless experiences that resonate with the mass market.

4. Network Effects at the Agent Level Will Separate AI Winners

Sustainable moats in AI assistants will come from multi-user network effects at the agent level, not single-player productivity. When autonomous assistants collaborate across teams to resolve queries and execute work, switching becomes increasingly difficult. Multiplayer workflows create organizational lock-in that personal assistants cannot replicate.

5. How Much of the Workload Stays at the Frontier Versus Open Weight?

AI application margins depend heavily on how much work requires expensive frontier models versus cheaper open weights. Complex reasoning may still demand frontier intelligence, while routine tasks like scheduling and email tagging continue moving down the cost curve. Shifting 80% of workloads to open weights over time could create far more sustainable economics.

6. My R&D Is Just Spent Getting Product Parity With the Giants

Competing with giants like OpenAI requires massive investment simply to maintain feature parity. Startups cannot rely on unique distribution if their underlying harness falls behind on core capabilities. AI assistants must invest heavily to match the execution speed and product depth of frontier teams.

7. Why Instinct Is Not a Competitor to Town

Consumer assistants like Instinct focus on rapid acquisition through subsidized personal tools, while enterprise platforms build monetizable team workflows. Although their technical harnesses may overlap, their target ICPs and business models diverge sharply. Enterprise agents monetize by embedding collaboration directly into daily operations.

(links below)

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Ryan Williams Verified account @RyanAWms · Jul 30

At @Cadre, I saw the gap firsthand. Large “institutional” firms built their own systems. But everyone else had to deliver with fewer resources, spreadsheets and manual work.

forbes.com/sites/jeffkauf…

“Institutional” should describe a standard, not a budget.

That conviction became @ellis_company

@JeffKauflin, @Forbes Ryan Williams’ Next Act After Cadre: A Fintech Fix For Private Credit’s Data Mess

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