Soham Sankaran

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@sohamsankaran

I run @PopVaxIndia (popvax.com) – we develop mRNA vaccines and therapeutics using computational protein design. I write at infinitesunrise.com

Hyderabad / Mumbai soh.am Joined August 2009

7K Following 10K Followers 7.4K Posts

Latest posts 5

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Soham Sankaran @sohamsankaran Oct 10

On August 31, the first two participants were injected with @PopVaxIndia’s first fridge-stable RNA vaccine candidate in a Phase I clinical trial in Australia. We built this vaccine at our RNA Foundry in Hyderabad – from computational design to GMP manufacturing. Here's how:

3:03

Soham Sankaran @sohamsankaran 6h

We’re making a personalized cancer vaccine for Yash, a 34 year-old pancreatic cancer patient, in the open with his consent.

We want external experts to review our design and make their own contributions before we manufacture it at the RNA Foundry.

RNAFoundry.com/yash

0:52

Soham Sankaran @sohamsankaran 1d

AI-designed viruses are coming, and our team @PopVaxIndia is building the Immune Engine to produce medicines against these threats within 4 weeks from sequencing. We're basing this work, led by @hcherzig, in London because of the UK's prescient vision in AI safety & biosecurity.

Just as @ukgov were the first government to establish an AI safety & security lab @AISecurityInst, they are now the first government to set up a dedicated organisation to combat the biosecurity risks created by generative AI, which require a different approach than natural threats.

We’ve been talking with the team building the AI Biosecurity Lab over the past few weeks, and we’re confident that they’re building an institution that is capable of meeting the enormous challenges that lie ahead. We look forward to working with them to help secure the world against the threat of AI-enabled bioweapons.

Kanishka Narayan MP @KanishkaNarayan Oct 23

2/7 We're launching a £165m National AI Biosecurity Initiative, including £100m for a world-first AI Biosecurity Lab.

This will harness British scientific expertise and latest AI to detect biological threats and protect people from emerging risks.

As with our @AISecurityInst, I want the new AIBL to lead the world in capability.
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Soham Sankaran @sohamsankaran 2d

Incredibly cool stuff!

hari_haran (building archgen YC F26) Verified account @HariAyapps 2d

@archgen_ is building skyscrapers for semiconductor chips

Shrinking transistors is getting harder. Stacking them makes heat harder to manage. We’re building the tools to design chips in three dimensions.

We stack transistors vertically, shorten connections, and optimize timing and heat together.

Our foundational model for thermal simulation, predicts temperature roughly 5,000× faster than conventional EDA tools.

Our placement engine ranked #1 in HRT’s macro-placement challenge

We’re working with some of the largest fabs in the world to tape out our first chip in April 2027

archgenlabs.com

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Soham Sankaran @sohamsankaran 2d

Everyone should read Nihal!

nihal @annihalated 2d

In Re:

a daily newsletter wherein I opine, digress, and declaim on all manner of balderdash, tripe, gobbledygook, nerdery, wonkery, baloney, and hogwash — in the time-worn format of 'letter to a friend.'

Intro email out in a few hours.

Subscribe at re.nihalsahu.net/?v2
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