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Brian Ferguson

@viropractor

We research innate immune sensing of viruses, immune evasion and vaccinology. Professor of viral immunity. Cambridge BSI representative @BSICambridge.
Cambridge, UK fergusonlab.path.cam.ac.uk Joined January 2009
4.6K Following 3.8K Followers 8.3K Posts

Latest posts 5

Brian Ferguson @viropractor
Fantastic to be part of this study that adds a new type of ubiquitin chain to the mechanism of pattern recognition receptor signalling. ANKIB1 is required for PRR-driven interferon production and has a broad impact on antiviral immunity. nature.com/articles/s4155…
www.nature.com Lysine-11 ubiquitination drives type-I/III interferon induction by cGAS–STING and Toll-like... Nature Cell Biology - Betrancourt, Cinko et al. identify ANKIB1-mediated K11 ubiquitination and OPTN recruitment as a shared mechanism for driving immune signalling by cGAS, TLR3 and TLR4, with...
Walczak Lab @Walczak_Lab Mar 6
Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin nature.com/articles/s4155…
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Brian Ferguson @viropractor
Tremendously crass to platform him at a time that measles cases are surging in the UK. bbc.co.uk/news/articles/…
www.bbc.co.uk Measles: Child dies at Alder Hey after contracting virus Seventeen children have been treated at the Liverpool hospital for the virus since June.
Dr Rachel Clarke Verified account @doctor_oxford Jul 13, 2025
Appalled to see the Telegraph giving Aseem Malhotra a platform today. He has spread increasingly dangerous vaccine misinformation with impunity.

⁦@gmcuk⁩’s failure to remove him from the register is every bit as appalling. A spineless dereliction of duty.
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Brian Ferguson @viropractor
"The most effective way to prevent the spread of measles is the MMR vaccine." Absolutely correct.
Secretary Kennedy Verified account @SecKennedy Apr 6, 2025
I came to­ Gaines County, Texas, today to comfort the Hildebrand family after the loss of their 8-year-old daughter Daisy. I got to know the family of 6-year-old Kayley Fehr after she passed away in February. I also developed bonds with and deep affection for other members of this community during that difficult time. My intention was to come down here quietly to console the families and to be with the community in their moment of grief.

I am also here to support Texas health officials and to learn how our HHS agencies can better partner with them to control the measles outbreak, which as of today, there are 642 confirmed cases of measles across 22 states, 499 of those in Texas.

In early March, I deployed a CDC team to bolster local and state capacity for response across multiple Texas regions, supply pharmacies and Texas run clinics with needed MMR vaccines and other medicines and medical supplies, work with local schools and healthcare facilities to support contact investigations, and to reach out to communities, including faith leaders, to answer any questions or respond to locations seeking healthcare. Since that time, the growth rates for new cases and hospitalizations have flattened. The most effective way to prevent the spread of measles is the MMR vaccine. I’ve spoken to Governor Abbott, and I’ve offered HHS’ continued support. At his request, we have redeployed CDC teams to Texas. We will continue to follow Texas’ lead and to offer similar resources to other affected jurisdictions.
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