Fantastic to be part of this study that adds a new type of ubiquitin chain to the mechanism of pattern recognition receptor signalling. ANKIB1 is required for PRR-driven interferon production and has a broad impact on antiviral immunity. nature.com/articles/s4155…
Excited to share our new work uncovering a previously unknown mechanism identifying ANKIB1 as the E3 ligase that writes a critical new letter of the ubiquitin code central for immune signalling: K11-linked ubiquitin nature.com/articles/s4155…View quoted post on X