Daniela Danková

@DankovaDaniela

@Astrazeneca Postdoc in Oligonucleotide Chemistry | @ChristianAOlsen lab alumni @UCPH_health | In the lab 🧪- on the court 🏀 - outdoors 🏞

Sweden Joined December 2011

329 Following 170 Followers 59 Posts

Latest posts 5

Pinned post

Daniela Danková @DankovaDaniela Dec 13, 2024

Happy to share the latest preprint from my PhD studies on the discovery of de novo macrocyclic inhibitors of HDAC11. This was a great collaboration between @christianaolsen lab (@carlosmyruela, @tnhansen) and Christian Heinis lab (@alexanderln).

Christian Adam Olsen @ChristianAOlsen Dec 10, 2024

New preprint @ChemRxiv on discovery of macrocyclic inhibitors of HDAC11 with the Christian Heinis @EPFL_CHEM_Tweet.

@DankovaDaniela, @alexanderln91, @CarlosMYruela, @HanseNrby, @UCPH_health

We thank @ERC_Research, @novonordiskfond, @DFF_raad for 💶

chemrxiv.org/engage/chemrxi…

View quoted post on X

Daniela Danková @DankovaDaniela Aug 20, 2024

After taking a few summer months to unwind after the PhD, I’m happy to share that I’m starting a new position as Postdoc in the Oligonucleotide Chemistry team at @AstraZeneca in Gothenburg, Sweden. Thrilled for the cool science that awaits!

Daniela Danková @DankovaDaniela Jun 10, 2024

I'm happy to share our News & Views article featured in @NatureChemistry, highlighting the excellent work on site-specific incorporation of glutarylated and succinylated lysine residues into multidomain proteins via genetic code expansion by @klanglab!

nature.com/articles/s4155…

www.nature.com Reversing the charge of lysine by genetic code expansion Nature Chemistry - Posttranslational modifications alter the structure and function of proteins. Now, genetic code expansion enables encoding of ε-N-succinyllysine and ε-N-glutaryllysine...

Daniela Danková @DankovaDaniela Apr 21, 2024

An eventful week is nearly over with our story now out in @JACS_Au : pubs.acs.org/doi/full/10.10…

pubs.acs.org Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of... Abstract. Multistep synthesis performed on solid support is a powerful means to generate small-molecule libraries for the discovery of chemical probes to d

Daniela Danková @DankovaDaniela Feb 12, 2024

In our latest preprint, we used SuFEx chemistry on solid phase for a quick and easy library synthesis of HDACis:

doi.org/10.26434/chemr…

This was a fun project started by Michael Bæk and developed by @HanseNrby and I, with great help from Erasmus student Linda Grlas! 1/8

View quoted post on X

Daniela Danková @DankovaDaniela Apr 19, 2024

Yesterday, surrounded by my mentors, colleagues, family and friends, I succesfully defended my PhD.

Many thanks to the assessment committee: Aubry Miller @DrugDiscov_DKFZ , Luca Laraia @laraialab and Bente Frølund for a really nice discussion and inspiring comments.