Georg Krainer

@GeorgKrainer

Research Group Leader in Molecular Biophysics @UniGraz | Senior Scientist & Founding Team Member #TransitionBio

University of Graz, Austria Joined October 2018

745 Following 494 Followers 146 Posts

Latest posts 5

Georg Krainer @GeorgKrainer Sep 5, 2024

🚀 Exciting news! 🚀

I’m thrilled to share that I’ve been awarded an ERC Starting Grant for my project SignAlloMod: Decoding the Molecular Logic of GPCR Signaling!

erc.europa.eu/news-events/ne…

erc.europa.eu ERC grants €780m to emerging science talent in Europe The European Research Council (ERC) has announced the award of 494 Starting Grants to young scientists and scholars across Europe. The funding - totalling nearly €780 million - supports cutting-edge...

Georg Krainer @GeorgKrainer Jul 14, 2023

📃Excited to share our preprint on single-molecule digital sizing of proteins. 🔥Highlights: sizing at fM concentrations, affinity profiling at the single-molecule level & sizing of polydisperse sample mixtures (oligomers, aggregates, nanoclusters)🚀🧪⤵️ biorxiv.org/content/10.110…

www.biorxiv.org Single-molecule digital sizing of proteins in solution Proteins constitute the molecular machinery of life and exert their biological function by interacting with other proteins, as well as by assembling into biomolecular complexes and higher order...

Georg Krainer @GeorgKrainer Apr 23, 2023

👇📰Check out our new paper "Surface patches induce nonspecific binding and phase separation of antibodies". 😎We looked at nonspecific binding of antibodies to DNA 🧬, and found that sticky surface patches can lead to antibody phase separation💦. doi.org/10.1073/pnas.2…

www.pnas.org Surface patches induce nonspecific binding and phase separation of antibodies | PNAS Nonspecific interactions are a key challenge in the successful development of therapeutic antibodies. The tendency for nonspecific binding of antib...

KnowlesLab Cambridge @KnowlesLabCamb Apr 21, 2023

Check out our new work in @PNASNews on how surface patches control protein binding specificity: doi.org/10.1073/pnas.2…
Great work by @HAusserwoeger, @GeorgKrainer, @TimWelsh_, @ElladeCsillery, Tomas, @SchneiderMatth and Therese in collaboration with @novonordisk and @CCG_MOE.
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Georg Krainer @GeorgKrainer Mar 2, 2023

Bored of laborious and time consuming single-well #smFRET measurements? Check out our recent preprint on multiwell plate #smFRET 👇 Great work led by @HartmannPHY @Schlierf_Lab biorxiv.org/content/10.110…

www.biorxiv.org Farewell to single-well: An automated single-molecule FRET platform for high-content, multiwell... Single-molecule FRET (smFRET) has become a widely used tool for probing the structure, dynamics, and functional mechanisms of biomolecular systems, and is extensively used to address questions...

Michael is feeling blue @Schlierf_Lab Mar 2, 2023

Farewell to single-well #smFRET. Our newest story on bioRxiv biorxiv.org/content/10.110… Great team work led by @HartmannPHY with @KoushikS33, Mathias, @nehagc18, Philipp and @GeorgKrainer. Brief tweetorial and open access software 1/5

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Georg Krainer @GeorgKrainer Feb 24, 2023

📃 Our latest work is out! Sizing of single proteins using nanofluidics. 🧪 Great collaboration with @BJacquat and many others @KnowlesLabCamb @ChemCambridge & in collaboration with #baumberglab,@KeyserLab & @group_laser pubs.acs.org/doi/10.1021/ac…

pubs.acs.org Single-Molecule Sizing through Nanocavity Confinement Abstract. An approach relying on nanocavity confinement is developed in this paper for the sizing of nanoscale particles and single biomolecules in solutio