Thank you Satchin and @WuTsaiAlliance for allowing us to participate in this exciting research🙏
A hidden gem in our exercise atlas: base-resolution single-nucleus DNA methylation maps of three muscle types, across male and female, sedentary and exercised mice. It’s the first resource of its kind in exercise research. Thank you @JoeEckerView quoted post on X
One outcome is a set of cell-type-specific methylation markers. For example, the long noncoding RNA LncPPARa is hypomethylated in progenitor cells.
Look up the methylation signature of your favorite gene here: neomorph.salk.edu/mouse-hpa/mous…
@WuTsaiAlliance @GeraldineMaier
cell.com/cell/abstract/…