Twitxy Saved

Anne Scheel

@annemscheel

Assistant prof at @UniUtrecht, trying to make science as reproducible as non-scientists think it is. Blogs at @the100ci. Now also on the app with nice weather.
Amsterdam, Nederland uu.nl/staff/amscheel Joined June 2011
1K Following 6.4K Followers 17K Posts

Latest posts 5

Pinned post

Anne Scheel @annemscheel
If you want X AND Y AND Z to be significant, you may even want to *increase* alpha for the individual comparisons to not lose power (and keep your overall alpha at the nominal level).
Which you should preregister of course, because people absolutely won’t buy it if you don’t.
I am afraid @stuartbuck1 is getting multiple comparisons wrong. If you want outcome X AND Y AND Z to be significant (as in the example) you do not correct so the problem never happens. You correct if you want X OR Y OR Z to show an effect.
View quoted post on X
Anne Scheel @annemscheel
New paper w/ @LeonidTiokhin & @lakens!
Registered Reports (RRs) are great for science b/c publication is guaranteed before results are known, reducing publication bias & QRPs. This supposedly also makes them great for *scientists*. But is that really true?
tinyurl.com/4sy993rr
www.biorxiv.org Career incentives make Registered Reports unattractive under realistic academic conditions Registered Reports are a publication format designed to reduce publication bias by guaranteeing publication before results are known. This guarantee is considered attractive in the prevailing...
Anne Scheel @annemscheel
Looks like a cool analysis, but note that it excludes preprints that were never published. So this last sentence in the abstract amounts to ‘conditioning on preprints accepted by the scientific community, preprints are good enough to be accepted by the scientific community’.
Ruslan Rust Verified account @rust_ruslan Jul 1
How much does a scientific claim actually change between the preprint and the final published paper?

We used a large language model to track it across all available 72,644 bioRxiv -> journal pairs from 2018 - 2025 in this new work with @HaoYin. 🧵
View quoted post on X
3 replies 6 reposts 15 likes 2.7K views View on X