@epigenetichulk
www.cell.com Single-cell multi-modal integrative analyses highlight functional dynamic gene regulatory networks... Holman et al. uncover distinct genetic programs driving human cardiomyocyte development, demonstrating how different developmental gene regulatory pathways lead to functional differences in cardiac... We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Amazing teamwork with @NilUresin, @_sabrinarichter, @fabian_theis, @erwinschoof, @Bo_PorseView quoted post on X
biorxiv.org/content/10.110…
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www.cell.com Super-enhancers include classical enhancers and facilitators to fully activate gene expression De novo construction of a multipartite enhancer unveils a new class of regulatory element referred to as “facilitators.” Facilitators lack intrinsic enhancer activity but enhance the activity of... 