@LoreofRunning

藤井 直人 Naoto Fujii Verified account @naotofuj · 2d

市民ランナーとエリートランナーで、マラソン中に必要な糖質摂取量は異なる？

ことを解説したIJSNEMの論文の一部 (Do Recreational Marathoners Need the Same In-Race Carbohydrate Recommendations as Elite Marathoners?)

以下の条件で理論モデルを比較
エリート（2時間で完走）
・体重：58 kg
・VO₂max：70
・運動強度：94%VO₂max
・糖質酸化率：84%
・推定糖質補給量：90 g/時（計180 g）

市民ランナー（4時間で完走）
・体重：75 kg
・VO₂max：40
・運動強度：60%VO₂max
・糖質酸化率：50%
・推定糖質補給量：53 g/時（計212 g）

エリートは運動強度が高く、1時間当たりの糖質補給量は約2倍

しかし市民ランナーは走行時間が長いため、レース全体で必要な糖質補給量は同程度

糖質補給は運動強度や走行時間に応じた調整が必要かも
journals.humankinetics.com/view/journals/…

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Massimo Verified account @Rainmaker1973 · 2d

A single bird has just accomplished one of the most extraordinary feats in the animal kingdom — flying nearly one-third of the way around the Earth without stopping to eat, drink, or rest.

The record-breaker is a five-month-old Bar-tailed Godwit that flew nonstop from Alaska to Tasmania, Australia. Covering 8,425 miles in just over 11 days, it set a new record for the longest nonstop flight ever documented in any bird.

What makes this journey even more astonishing is that it was the young godwit’s very first migration. The entire route took place over the open Pacific Ocean, with no chance to land. Despite that, the bird navigated thousands of miles of featureless water with pinpoint accuracy.

This incredible endurance is made possible by remarkable physiological adaptations. Before takeoff, the godwit packs on enormous fat reserves — nearly half its body weight — to fuel the flight. At the same time, many of its internal organs, including parts of the digestive system, temporarily shrink to lighten the load and maximize energy efficiency.

Unlike many seabirds that depend heavily on gliding, this godwit flapped continuously for the entire journey, battling shifting winds and weather systems the whole way.

Researchers at the Pūkōroro Auckland Shorebird Centre say discoveries like this are transforming our understanding of migratory birds. Their astonishing endurance, navigation skills, and energy management demonstrate biological capabilities that can match — and in some ways surpass — even the most advanced human engineering.

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Whitfield Lewis, MD 🇦🇬🇺🇸 Verified account @whitfieldlewis6 · Nov 4

Why does one 50-year-old have extensive ASCVD despite a lifelong LDL of 90 mg/dL, while another has no clinically meaningful atherosclerosis despite an LDL of 160 mg/dL?

Beyond genetics and family history, what explains this discrepancy?

The Framingham Heart Study was among the earliest major studies to investigate this question.

A 2025 study provides further insight:

Individual risk factors:

Elevated LDL-C alone: 35% higher cardiovascular hazard
Elevated SBP (>140 mmHg) alone: 29% higher
Smoking alone: 69% higher

When combined:

LDL-C + elevated SBP: 79% higher
LDL-C + smoking: 126% higher
Smoking + elevated SBP: 118% higher
All three combined: 197% higher

Interestingly, smoking alone was associated with a substantially higher cardiovascular hazard than elevated LDL-C alone.

This aligns with what I observe in clinical practice. Some of the most severe cases of ASCVD I’ve encountered have been in smokers, many of whom had normal or even low LDL-C levels.

And we haven’t even considered insulin resistance, triglyceride-rich lipoproteins, central obesity, and other metabolic abnormalities.

LDL matters, but it doesn’t operate in isolation.

#FOAMed

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George Kusche @GeorgeKusche · Nov 5

@ProfTimNoakes Tim, I would love to work with you to see if I can run low 2 hours in the marathon. Please let me know how we can get in touch.

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